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Beyond gastrointestinal effects, certain anti-obesity drugs modulate peripheral metabolism to improve glucoselipid homeostasis and increase energy expenditure [Figure 4]

Persistent mitochondrial hyperpolarization, increased reactive oxygen intermediate production, and cytoplasmic alkalinization characterize altered IL-10 signaling in patients with systemic lupus erythematosus

ROS accumulation is positively correlated with pancreatic fibrosis in both acinar and islet tissues, confirming the role of OxS in fibrosis onset [36]

doi: 10.1210/jc.2002-021558 23 GiordanoRPicuAMarinazzoEDAngeloVBerardelliRKaramouzisIet al

doi: 10.1080/17425255.2021.1925249